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Preparation of N-[(purin-6-ylthio)acetyl] amino acids

  • E. D. Kaverzneva
  • V. K. Zvorykina
  • V. V. Kiseleva
Organic and Biological Chemistry
  • 20 Downloads

Conclusions

By the action of chloroacetyl derivatives of amino acids and their esters on purine-6-thiol in an aqueous medium in presence of alkaline agents the following substances were obtained: N-[(purin-6-ylthio)acetyl]alanine, N-[(purin-6-ylthio)acetyl]valine, N-[(purin-6-ylthio)acetyl]leucine, 3-phenyl-N-[(purin-6-ylthio)acetyl]alanine, and 3-phenyl-N-[(purm-6-ylthio)acetyl]-β-alanine and their esters.

Keywords

Ester Alanine Leucine Acetyl Aqueous Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    Ch. E. Carter, J. biol. chem.,223, 139 (1956).Google Scholar
  2. 2.
    H. Lettré and H. Ballweg, Liebigs Ann. Chem.,633, 171 (1960).Google Scholar
  3. 3.
    A. Ballio and V. Di Vittorio, Gazz. chim. ital.,90, 501 (1960).Google Scholar
  4. 4.
    D. N. Ward, J. Wade, E. F. Wallborg, and T. S. Osdene, J. Organ. Chem.,26, 5000 (1961).Google Scholar
  5. 5.
    C. Huber, Angew. Chem.,68, 706 (1956).Google Scholar
  6. 6.
    Ch. G. Skinner, J. R. Glaybrook, D. L. Ross, and W. Shive, J. Organ. Chem,23, 1223 (1958).Google Scholar
  7. 7.
    G. B. Elion, I. Goodman, W. Lange, and G. H. Hitchings, J. Amer. Chem. Soc.,81, 1898 (1959).Google Scholar
  8. 8.
    M. Semonsky, A. Cerny, and V. Jelinek, Czech.92, 287, okt, 15 (1959); Chem. Abstrs.,55, 16576 b (1961).Google Scholar
  9. 9.
    E. Ronwin, J. Organ. Chem.,18, 127 (1953).Google Scholar
  10. 10.
    W. S. Fönes, J. Organ. Chem.,17, 1661 (1952).Google Scholar

Copyright information

© Consultants Bureau 1967

Authors and Affiliations

  • E. D. Kaverzneva
    • 1
  • V. K. Zvorykina
    • 1
  • V. V. Kiseleva
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRUSSR

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