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Journal of Behavioral Medicine

, Volume 11, Issue 1, pp 59–69 | Cite as

Defining anticipatory nausea and vomiting: Differences among cancer chemotherapy patients who report pretreatment nausea

  • Michael A. Andrykowski
Article

Abstract

It is important to distinguish patients whose reports of pretreatment nausea and vomiting reflect classically conditioned anticipatory nausea and vomiting (ANV) from those whose reports reflect the influence of other pharmacological and psychological factors. Therefore, Andrykowski (J. Behav. Med.9: 33–41, 1986) has suggested that only patients who report pretreatment nausea on Day 1 of a chemotherapy cycle be considered to have developed ANV. As part of a prospective, longitudinal investigation of side effects associated with cancer chemotherapy, three groups of patients were identified: those who (a) never reported pretreatment nausea (noPTN), (b) reported pretreatment nausea but never prior to a Day 1 infusion (PTN), and (c) reported pretreatment nausea prior to a Day 1 infusion (PTND1). Discriminant analysis revealed that the PTN and noPTN groups did not differ, while both differed from the PTND1 group, particularly with respect to factors presumed to facilitate classical conditioning. The results justify excluding PTN patients from the criterion group of patients considered to have developed ANV.

Key words

cancer pretreatment nausea anticipatory nausea vomiting 

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References

  1. Andrykowski, M. A. (1986). Definitional issues in the study of anticipatory nausea in cancer chemotherapy.J. Behav. Med. 9: 33–41.PubMedGoogle Scholar
  2. Andrykowski, M. A. (1987). Do infusion-related tastes and odors facilitate the development of anticipatory nausea? A failure to support hypothesis.Health Psychol. 6: 329–341.PubMedGoogle Scholar
  3. Andrykowski, M. A., and Redd, W. H. (1987). Longitudinal analysis of the development of anticipatory nausea.J. Consult. Clin. Psychol. 55: 36–41.PubMedGoogle Scholar
  4. Andrykowski, M. A., Redd, W. H., and Hatfield, A. K. (1985). Development of anticipatory nausea: A prospective analysis.J. Consult Clin. Psychol. 53: 447–454.PubMedGoogle Scholar
  5. Burish, T. G., and Carey, M. P. (1986). Conditioned aversive responses in cancer chemotherapy patients: Theoretical and developmental analysis.J. Consult. Clin. Psychol. 54: 593–600.PubMedGoogle Scholar
  6. Burish, T. G., Redd, W. H., and Carey, M. P. (1985). Conditioned nausea and vomiting in cancer chemotherapy: Treatment approaches. In Burish, T. G., Levy, S. M., and Meyerowitz, B. E. (eds.),Cancer, Nutrition, and Eating Behavior: A Biobehavioral Perspective, Lawrence Earlbaum, Hillsdale, NJ, pp. 205–224.Google Scholar
  7. Eysenck, H. J. (1963).Manual for the Eysenck Personality Inventory, Educational and Industrial Testing Service, San Diego, CA.Google Scholar
  8. Fetting, J. H., Grochow, L. B., Folstein, M. F., Ettinger, D. S., and Colvin, M. (1982). The course of nausea and vomiting after high-dose cyclophosphamide.Cancer Treat. Rep. 66: 1487–1493.PubMedGoogle Scholar
  9. Katz, E. R. (1982). Conditioned aversion to chemotherapy (letter).Psychosomatics 23: 650–651.PubMedGoogle Scholar
  10. Morrow, G. R. (1982). Prevalence and correlates of anticipatory nausea and vomiting in chemotherapy patients.J. Natl. Cancer Inst. 68: 484–488.Google Scholar
  11. Nesse, R. M., Carli, T., Curtis, G. C., and Kleinman, P. D. (1980). Pretreatment nausea in cancer chemotherapy: A conditioned response?Psychosom. Med. 42: 33–36.PubMedGoogle Scholar
  12. Nicholas, D. R. (1982). Prevalence of anticipatory nausea and emesis in cancer chemotherapy patients.J. Behav. Med. 5: 461–463.PubMedGoogle Scholar
  13. Nei, N. H., Hull, C. H., Jenkins, J. G., Steinbrenner, K., and Bent, D. H. (1975).Statistical Package for the Social Sciences, McGraw-Hill, New York.Google Scholar
  14. Redd, W. H., and Andrykowski, M. A. (1982). Behavioral intervention in cancer treatment: Controlling aversion reactions to chemotherapy.J. Consult. Clin. Psychol. 50: 1018–1029.PubMedGoogle Scholar
  15. Redd, W. H., Andresen, G. V., and Minagawa, R. V. (1982). Hypnotic control of anticipatory emesis in patients receiving cancer chemotherapy.J. Consult. Clin. Psychol. 50: 14–19.PubMedGoogle Scholar
  16. Redd, W. H., Burish, T. G., and Andrykowski, M. A. (1985). Aversive conditioning and cancer chemotherapy. In Burish, T. G., Levy, S. M., and Meyerowitz, B. E. (eds.),Cancer, Nutrition, and Eating Behavior: A Biobehavioral Perspective, Lawrence Earlbaum, Hillsdale, NJ, pp. 117–132.Google Scholar
  17. Riley, A. L., and Tuck, D. L. (1985). Conditioned taste aversion: A bibliography.Ann. N. Y. Acad. Sci, 443: 381–437.PubMedGoogle Scholar
  18. Spielberger, C. D., Gorsuch, R. L., and Lushene, R. E. (1970).Test Manual for the State-Trait Anxiety Inventory, Consulting Psychologists Press, Palo Alto, CA.Google Scholar
  19. van Komen, R. W., and Redd, W. H. (1985). Personality factors associated with anticipatory nausea/vomiting in patients receiving cancer chemotherapy.Health Psychol. 4: 189–202.PubMedGoogle Scholar
  20. Weddington, W. W. (1982). Psychogenic nausea and vomiting associated with cancer chemotherapy.Psychother. Psychosom. 37: 129–136.PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • Michael A. Andrykowski
    • 1
  1. 1.Department of Behavioral ScienceUniversity of Kentucky College of MedicineLexington

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