Summary
The author studied the effect of ultrasonic waves of high intensity on the growth and metastasis of Brown-Pearce's tumor. The rabbits were acted upon by sound waves in 7–15 days after inoculation of the tumor.
It was shown that single action by ultrasonic waves of high intensity (80–150 w/cm2) at the frequency of 1500 kcps of short duration (3–1.3 seconds) results in the resolution of the Brown-Pearce tumor inoculated into the muscle or the testicle in 40–50% of the cases (in certain experiments in 60–70% of the cases) in the surrounding normal tissue is not disturbed under these conditions.
The resolution of the tumor acted upon by the ultrasonic waves is connected in a number of cases with the disintegration of metastases which were not acted upon by sound.
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Dmitrieva, N.P. The effect of high intensity ultrasound on the growth and metastasization of inoculated brown-pearce tumors in rabbits. Bull Exp Biol Med 46, 1383–1388 (1958). https://doi.org/10.1007/BF00845187
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DOI: https://doi.org/10.1007/BF00845187