Summary
The method of anaphylaxis with desensitization makes it possible to analyze the antigenic properties of the heterotransplanted tumors in guinea pigs with considerable precision. It was demonstrated that the temporary growth of the mouse tumor in an animal of another species does not alter considerably its antigenic properties. The antigens of the original tumor, particularly the antigen characterizing the species specificity of the protein are preserved in the heterotransplant of the tumor in these conditions.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
V. K. Kozlov, Biull. Eksptl. Biol. i Med. 37, 4, 56–59 (1954).
G. V. Suvorova, Biull. Eksptl. Biol. i Med. No. 1, 82–85 (1957). See English translation.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kozlov, V.K. The use of the method of anaphylaxis with desensitization for the study of the antigenic properties of tumors during heterotransplantation. Bull Exp Biol Med 46, 1362–1367 (1958). https://doi.org/10.1007/BF00845182
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00845182