Summary
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1.
Some new derivatives of amines, amino acids, and peptides containing bis-1-aziridinylphosphinyl groups were prepared.
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2.
Bis-1-aziridinylphosphinyl and bis-1-aziridinylphosphinothioyl groups can be introduced by the direct phosphorylation of amines and their derivatives with the aid of bis-1-aziridinylphosphinyl chloride and bis-1-aziridinylphosphinothioyl chloride.
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I. L. Knunyants, O. V. Kil'disheva, N. E. Golubeva, and S. Zurabyan, DAN SSSR,142, 370 (1962).
O. Friedman et al., J. Med. Chem.,6, 449 (1963).
Z. V. Popova and V. G. Nemets, Tr. Leningr. tekhn. inst.,40, 180 (1957).
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This article is published in accordance with a resolution of the Conference of Editors-in-Chief of Journals of the Academy of Sciences of the USSR of July 12, 1962, as a dissertation paper by S. É. Zurabyan.
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya No. 11, pp. 2036–2042, November, 1964
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Zurabyan, S.É., Keblas, S.S. & Knunyants, I.L. Cancerolytic peptides with directed action. Russ Chem Bull 13, 1932–1936 (1964). https://doi.org/10.1007/BF00844490
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DOI: https://doi.org/10.1007/BF00844490