Skip to main content
SpringerLink
Log in

Microbiological transformations of steroids

4. Oxidation of pregnenolone [3\-hydroxypregn-5-en-20-one] with the aid of rhizopus nigricans VNIKhFl-7

  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Summary

  1. 1.

    In the fermentation of 3β -hydroxypregn-5-en-20-one with a culture of Rhizopus nigricans VNIKhFI-7, 3α,7α,11α -trihydroxypregn-5-en-20-one and 3β,11α -dihydroxypregn-5-ene-7,20-dione are formed.

  2. 2.

    3β -7α,11α. -Trihydroxypregn-5-en-20-one is converted extremely readily into 3β,11β-dihydroxypregn-5-ene-7, 20-one.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. H. C. Murray and D. H. Peterson, US Patent 2702809 (1955); Chem. Abstrs.,50, 26916 (1956).

    Google Scholar 

  2. S. H. Eppstein, P. D. Meister, H. C. Murray, and D. H. Peterson, Vitamins and Hormones,14, 359 (1956); (Academic Press, Inc., New York).

    Google Scholar 

  3. R. M. Dodson, R. T. Nicholson, and R. D. Muir, J. Am. Chem. Soc.,81, 6295 (1959).

    Google Scholar 

  4. T. Asai, K. Aida, E. Ohki, T. Tanaka, and M. Hattori, Nippon Nogei Kagaku Kaishi,32, 723 (1958).

    Google Scholar 

  5. D. N. Kirk, V. Petrov, and M. N. Williamson, J. Chem. Soc.,1960, 387.

  6. A. S. Barmenkov and E. G. Balasheva, Med. Prom. SSSR, No. 7, 45 (1962).

    Google Scholar 

  7. L. F. Fieser and M. Fieser, Steroids (Reinhold Publishing Corp., New York, 1959), p. 170.

    Google Scholar 

  8. C. Djerassi, Dispersion of Optical Rotation [Russian translation] (IL, Moscow, 1962), p. 170.

    Google Scholar 

  9. L. F. Fieser and M. Fieser, Steroids (Reinhold Publishing Corp., New York, 1959), p. 566.

    Google Scholar 

  10. A. Schubert, K. Heller, and R. Sieben, Tetrahedron,18, 998 (1962).

    Google Scholar 

  11. V. M. Potapov and A. P. Terent'ev, Zh. obshch. khimii,31, 1003 (1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for the Chemistry of Natural Products, Academy of Sciences of the USSR, USSR

    Leonid M. Kogan, É. A. Elin, A. S. Barmenkov & I. V. Torgov

Authors
  1. Leonid M. Kogan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. É. A. Elin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. S. Barmenkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. I. V. Torgov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya No. 11, pp. 2016–2021, November, 1964

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kogan, L.M., Elin, É.A., Barmenkov, A.S. et al. Microbiological transformations of steroids. Russ Chem Bull 13, 1914–1918 (1964). https://doi.org/10.1007/BF00844487

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00844487

Keywords

Search

Navigation