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Glycopeptides

Communication 6. Further development of the synthesis of N-amino-acyl derivatives of amino sugars
  • N. V. Molodtsov
  • N. K. Kochetkov
  • V. A. Derevitskaya
Organic and Biological Chemistry
  • 22 Downloads

Summary

  1. 1.

    A new method of preparing N-(amino-acyl) derivatives is extended to the preparation of N-(amino-acyl) derivatives of D-glucosamine containing residues of proline, L-tyrosine, and 6-aminohexanoic acid.

     
  2. 2.

    On the basis of the same method two variants are developed for the synthesis of N-peptide derivatives of amino sugars by the condensation of the amino sugar with the benzyloxycarbonyl derivative of the peptide and by the gradual building up of a peptide chain on an N-(amino-acyl) derivative of the amino sugar. In this way N-di-glycyi-, N-triglycyl-, and N-(L-alanylglycyl)-glucosamines were prepared.

     

Keywords

Peptide Sugar Proline Glucosamine Glycopeptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    N. K. Kochetkov, V. A. Derevitskaya, and N. V. Molodtsov, Chem. and Industr., 1961, 1159.Google Scholar
  2. 2.
    N. K. Kochetkov, V. A. Derevitskaya, and N. V. Molodtsov, Zh. obshch. khimii,32, 2500 (1962).Google Scholar
  3. 3.
    N. K. Kochetkov, V. A. Derevitskaya, L. M. Likhosherstov, M. V. Molodtsov, and S. G. Kara-Murza, Tetrahedron,18, 273 (1962).Google Scholar
  4. 4.
    V. A. Derevitskaya, L. M. Likhosherstov, and N. K. Kochetkov, Izv. AN SSSR. Otd. khim. n., 1962, 1795.Google Scholar
  5. 5.
    N. K. Kochetkov, V. A. Derevitskaya, and L. M. Likhosherstov, Izv. AN SSSR. Otd. khim. n., 1963, 688.Google Scholar

Copyright information

© Consultants Bureau Enterprises, Inc. 1964

Authors and Affiliations

  • N. V. Molodtsov
    • 1
  • N. K. Kochetkov
    • 1
  • V. A. Derevitskaya
    • 1
  1. 1.Institute for the Chemistry of Natural ProductsAcademy of SciencesUSSR

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