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Chemistry of Heterocyclic Compounds

, Volume 21, Issue 12, pp 1377–1381 | Cite as

Derivatives of 2,3-dihydpo-1H-1,5-benzodiazepine based on substituted 1,2-phenylenediamines and acetylarenes

  • V. D. Orlov
  • S. M. Desenko
Article
  • 24 Downloads

Abstract

Derivatives of 2,3-dihydro-1H-1,5-benzodiazepine were obtained by the reaction of 4-chloro-, 4-bromo- 3,5-dichloro-, and 4-cyano-substituted ortho-phenyl-enediamines with 4-R-acetophenones in the presence of concentrated sulfuric acid. Electron-withdrawing groups R increase the reaction rate and consequently promote the formation of a mixture of isomeric products. The structure of the compounds and the composition of their mixtures were established by PMR spectroscopy. The reaction mechanism is discussed.

Keywords

Spectroscopy Organic Chemistry Sulfuric Acid Reaction Mechanism Concentrate Sulfuric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • V. D. Orlov
    • 1
  • S. M. Desenko
    • 1
  1. 1.A. M. Gor'kii State UniversityKhar'kov

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