Gastroesophageal reflux scintigraphy with radioactive capsules — a new technique for detection and quantitation of reflux
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A new technique for performing quantitative gastroesophageal scintigraphy has been described. The method involves administration of radioactivity in capsule form into the stomach; the isotope is released after dissolution of the capsule. The mean time of onset of capsule breakage was 3.3 min (range 2–5 min) and complete dissolution occurred by 6.0 min (range 5–8 min). The appearance of isotope activity in the oesophagus by means of cine scintigraphy was quantified by PDP 11/34 computer (Gamma-11) in terms of percentage of gastroesophageal reflux (GER). In 15 healthy subjects, the percentage of reflux (mean ±S.D.) in the lower, middle and upper oesophagus was found to be 1.25±0.67, 0.26±0.23 and 0.02±0.04 respectively. We have studied 52 patients using this technique, and results are encouraging.
Key wordsGastroesophageal reflux Radioactive Capsule Physiological Non-invasive Quantitation
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- Fisher RS, Cohen S (1978) Gastroesophageal reflux. Med Clin North Am 62:3–20Google Scholar
- Kaul B, Petersen H, Grette K, Erichsen H, Myrvold HE (1985) Scintigraphy, pH measurement & radiography to the evaluation of gastroesophageal reflux. Scand J Gastroenterol 20:289–294Google Scholar
- Leon S, Robert CF (1981) Scintigraphic evaluation of disorders of the esophagus, stomach and duodenum. Med Clin North Am 65:1291–1308Google Scholar
- Malmud LS, Fisher RS (1981) Scintigraphic evaluation of disorders of the esophagus, stomach & duodenum. Med Clin North Am 65:1291–1308Google Scholar
- Paul FW, Torn RD (1981) Foregut motor disorder & their surgical management. Med Clin North Am 65:1235–1268Google Scholar