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European Journal of Nuclear Medicine

, Volume 16, Issue 4–6, pp 345–348 | Cite as

Gastroesophageal reflux scintigraphy with radioactive capsules — a new technique for detection and quantitation of reflux

  • P. S. Soni
  • C. Sarojini
  • B. A. Krishna
Original Article

Abstract

A new technique for performing quantitative gastroesophageal scintigraphy has been described. The method involves administration of radioactivity in capsule form into the stomach; the isotope is released after dissolution of the capsule. The mean time of onset of capsule breakage was 3.3 min (range 2–5 min) and complete dissolution occurred by 6.0 min (range 5–8 min). The appearance of isotope activity in the oesophagus by means of cine scintigraphy was quantified by PDP 11/34 computer (Gamma-11) in terms of percentage of gastroesophageal reflux (GER). In 15 healthy subjects, the percentage of reflux (mean ±S.D.) in the lower, middle and upper oesophagus was found to be 1.25±0.67, 0.26±0.23 and 0.02±0.04 respectively. We have studied 52 patients using this technique, and results are encouraging.

Key words

Gastroesophageal reflux Radioactive Capsule Physiological Non-invasive Quantitation 

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References

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • P. S. Soni
    • 1
  • C. Sarojini
    • 1
  • B. A. Krishna
    • 1
  1. 1.Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre AnnexeParel, BombayIndia

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