Skip to main content
Log in

Pretreatment of aDrosophila simulans mutant line with benz(a)pyrene induces an aberrant isoform of cytochrome P-450 with increased ability to metabolize benz(a)pyrene

  • Experimental Genetics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literature Cited

  1. I. I. Karuzina and A. I. Archakov, Modern Methods in Biochemistry [in Russian], Moscow (1977), p. 49.

  2. V. V. Lyakhovich and I. B. Tsyrlov, Induction of Enzymes of Xenobiotic Metabolism [in Russian], Novosibirsk (1981), p. 173.

  3. E. G. Ugnivenko, S. Yu. Fuks, R. D. Safaev, et al., Range and Methods of Genotoxic Assessment and Side Effects of Biologically Active Substances [in Russian], Leningrad (1989), p. 94.

  4. S. Yu. Fuks and G. A. Belitskii, Vopr. Onkol., No. 8, 911 (1990).

    Google Scholar 

  5. P. W. Albro, Analyt. Biochem.,65, 485 (1975).

    Google Scholar 

  6. P. M. Dansette, G. C. Du Bois, and D. M. Kerina, Analyt. Biochem.,97, 340 (1979).

    PubMed  Google Scholar 

  7. W. Dehnen, R. Tomingas, and J. Roos, Analyt. Biochem.,53, 373 (1973).

    PubMed  Google Scholar 

  8. W. H. Habig, M. J. Pabst, and W. B. Jakoby, J. Biol. Chem.,249, 7130 (1974).

    PubMed  Google Scholar 

  9. I. Hällstrom, A. Blanck, and S. Atuma, Biochem. Pharmacol.,33, 13 (1984).

    PubMed  Google Scholar 

  10. U. K. Laemmli, Nature,227, 680 (1970).

    PubMed  Google Scholar 

  11. S. Omura and R. Sato, J. Biol. Chem.,239, 2379 (1964).

    PubMed  Google Scholar 

  12. J. E. Sinclair, J. F. Healey, R. McAllister, et al., Analyt. Biochem.,114, 316 (1981).

    PubMed  Google Scholar 

  13. B.-J. Song, R. L. Veech, S. S. Park, et al., J. Biol. Chem.,264, 3568 (1989).

    PubMed  Google Scholar 

  14. J. A. Hijlstra and E. W. Vagel. Mutat. Res.125, 243 (1984).

    PubMed  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fuks, S.Y., Shpigel'man, V.S., Safaev, R.D. et al. Pretreatment of aDrosophila simulans mutant line with benz(a)pyrene induces an aberrant isoform of cytochrome P-450 with increased ability to metabolize benz(a)pyrene. Bull Exp Biol Med 112, 1173–1176 (1991). https://doi.org/10.1007/BF00839570

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00839570

Key Words

Navigation