Advertisement

European Journal of Nuclear Medicine

, Volume 22, Issue 2, pp 154–157 | Cite as

Anterior, posterior, left anterior oblique, and geometric mean views in gastric emptying studies using a glucose solution

  • William T. Phillips
  • C. Alex McMahan
  • J. C. Lasher
  • Michael R. Blumhardt
  • Joyce G. Schwartz
Short Communication

Abstract

Previous research has shown that the single anterior view of the stomach overestimates the gastric half-emptying time of a solid meal compared to the geometric mean of the anterior and posterior views. Little research has been performed comparing the various views of gastric emptying of a glucose solution. After an overnight fast, 49 nondiabetic subjects were given a 450 ml solution containing 50 g of glucose and 200 Ci of technetium-99m sulfur colloid. Sequential 1-min anterior, posterior, and left anterior oblique views were obtained every 15 min. The mean percent solution remaining in the stomach for all three views differed from the geometric mean by 1.9% or less at all time points. Average gastric half-emptying times were: geometric mean, 62.7±3.3 min; anterior, 61.9±3.2 min; posterior, 63.5±3.5 min; and left anterior oblique, 61.6±3.3 min. These half-emptying times were not statistically different. For individual patients, differences between all three views and the geometric mean were not clinically important. Approximately 95% of all patients are expected to have gastric half-emptying times measured by any of the three single views within 17 min of the gastric half-emptying time obtained using the geometric mean. The imaging of gastric emptying using glucose solutions can be performed using a convenient single view which allows continuous dynamic imaging.

Key words

Gastric emptying Dynamic imaging Geometric mea 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Liddle RA, Morita ET, Conrad CK, Williams JA. Regulation of gastric emptying in humans by cholecystokinin.J Clin Invest 1986; 77: 992–996.Google Scholar
  2. 2.
    Phillips WT, Schwartz JG, Blumhardt R, McMahan CA. Linear gastric emptying of hyperosmolar glucose solutions.J Nucl Med 1991; 32: 377–381.Google Scholar
  3. 3.
    Phillips WT, Schwartz JG, McMahan CA. Rapid gastric emptying of an oral glucose solution in type 2 diabetic patients.J Nucl Med 1992; 33: 1496–1500.Google Scholar
  4. 4.
    Phillips WT, Schwartz JG, McMahan CA. Reduced postprandial blood glucose levels in recently diagnosed non-insulindependent diabetes secondary to pharmacologically induced delayed gastric emptying.Dig Dis Sci 1993; 38: 51–58.Google Scholar
  5. 5.
    Robinson PH, Clarke M, Barrett J. Determinants of delayed gastric emptying in anorexia nervosa and bulimia nervosa.Gut 1988; 29: 458–464.Google Scholar
  6. 6.
    Oster-Jorgensen E, Pedersen SA, Larsen ML. The influence of induced hyperglycaemia on gastric emptying rate in healthy humans.Scand J Clin Lab Invest 1990; 50: 831–836.Google Scholar
  7. 7.
    Brener W, Hendrix TR, McHugh PR. Regulation of the gastric emptying of glucose.Gastroenterology 1983; 85: 76–82.Google Scholar
  8. 8.
    Kelly KA. Gastric emptying of liquids and solids: roles of proximal and distal stomach.Am J Physiol 1980; 239: G71-G76.Google Scholar
  9. 9.
    Fahey FH, Ziessman HA, Collen MJ, Eggli DF. Left anterior oblique projection and peak-to-scatter ratio for attenuation compensation of gastric emptying studies.J Nucl Med 1989; 30: 233–239.Google Scholar
  10. 10.
    Moore JG, Christian PE, Taylor AT, Alazraki N. Delayed and complex emptying patterns without appropriate correction.J Nucl Med 1985; 26: 1206–1210.Google Scholar
  11. 11.
    Bland M, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement.Lancet 1986; I: 307–310.Google Scholar
  12. 12.
    Conover WJ.Practical nonparametric statistics. New York: Wiley Press, 1971.Google Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • William T. Phillips
    • 1
  • C. Alex McMahan
    • 2
  • J. C. Lasher
    • 1
  • Michael R. Blumhardt
    • 2
  • Joyce G. Schwartz
    • 2
  1. 1.Department of RadiologyThe University of Texas Health Science Center at San AntonioSan AntonioUSA
  2. 2.Department of PathologyThe University of Texas Health Science Center at San AntonioSan AntonioUSA

Personalised recommendations