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Structural changes in the rat myocardium during adaptation to mountain hypoxia

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Changes in weight indices for different parts of the heart, the area of cross sections of the myocytes, and vascularization of the myocardium during adaptation to hypoxia were studied in experiments on rats exposed to high-altitude hypoxia (3200 m above sea level). The morphological manifestation of compensatory and adaptive reactions of the rat heart to hypoxia is an increase in its weight, chiefly on account of hypertrophy of the myocardium of the right ventricle. Increasing hypertrophy of the myocardium is accompanied by the corresponding increase in its vascularization.

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Kononova, V.A. Structural changes in the rat myocardium during adaptation to mountain hypoxia. Bull Exp Biol Med 88, 1228–1231 (1979). https://doi.org/10.1007/BF00838216

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  • DOI: https://doi.org/10.1007/BF00838216

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