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Chromosomal aberrations in embryonic liver and bone marrow cells of A/He and C57BL/6 mice induced by thiotepa

  • Experimental Genetics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Chromosomal aberrations in the first mitosis of embryonic liver and bone marrow cells were studied in A/He and C57Bl/6 mice after injection of the alkylating agent thioTEPA in the g1-S period of the cell cycle. Chromosomes of A/He mice were shown to be more sensitive to the mutagenic action of the compound.

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Literature Cited

  1. N. P. Bochkov, Yu. S. Demin, and N. V. Luchnik, Genetika, No. 8, 133 (1972).

    Google Scholar 

  2. A. A. Zavarzin, DNA Synthesis and the Kinetics of Cell Populations in Mammalian Ontogeny [in Russian], Leningrad (1967).

  3. Yu. V. Korogodina and I. G. Lil'p, Tsitol. Genet., No. 12, 134 (1978).

    Google Scholar 

  4. V. N. Orlov, G. A. Chudinvoskaya, and E. P. Kryukova, Investigation of Mammalian Chromosome Sets [in Russian], Moscow (1976).

  5. N. A. Plokhinskii, Algorithms in Biometrics [in Russian], Moscow (1967).

  6. N. I. Surkova and A. M. Malashenko, Genetika, No., 10, 81 (1974).

    Google Scholar 

  7. S. Brecher, Mutat. Res.,42, 249 (1977).

    Google Scholar 

  8. P. K. Datta, H. Frigger, and E. Schleiermcher, Chemical Mutagenesis in Mammals and Man, New York (1970).

  9. A. K. Dubey, S. Sarkar, and R. N. Shah, Ind. J. Exp. Biol.,13, 65 (1975).

    Google Scholar 

  10. E. H. M. Ford and D. H. M. Woollam, Stain Technol.,38, 271 (1963).

    Google Scholar 

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Korogodina, Y.V., Gordeeva, E.V. & Lil'p, I.G. Chromosomal aberrations in embryonic liver and bone marrow cells of A/He and C57BL/6 mice induced by thiotepa. Bull Exp Biol Med 88, 1182–1184 (1979). https://doi.org/10.1007/BF00838201

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  • DOI: https://doi.org/10.1007/BF00838201

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