Abstract
The DNA content on populations rich in T- and B-cells and the numerical ratio between these cells in lymph nodes of intact mice and mice with tumors were investigated in experiments on BALB/c mice with a progressively growing sarcoma induced by Moloney virus. The fraction rich in T-lymphocytes characteristically had a higher DNA content than the fraction consisting mainly of B-lymphocytes. Development of the tumor led to a decrease in the relative number of macronucleolar lymphocytes and a simultaneous increase in the number of micronucleolar lymphocytes in the lymph nodes, especially the regional nodes.
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Gudim-Levkovich, K.A., Yudin, V.M., Lysyuk, L.P. et al. Cell composition of lymph nodes and DNA content in their various lymphocyte populations in mice with tumors induced by Moloney mouse sarcoma virus. Bull Exp Biol Med 88, 1173–1175 (1979). https://doi.org/10.1007/BF00838198
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DOI: https://doi.org/10.1007/BF00838198