Abstract
Ability to form hematopoietic cell colonies from the yolk sac and limb bud of a quail embryo at the 60 h incubation stage (i.e., before establishment of a closed circulation) was studied in the bone marrow of sublethally irradiated 3-week-old chicks. The experimental results are based on the ability to distinguish between quail and chick cells by means of a natural marke (Feulgen-positive nucleolus). After transplantation of limb bud cells roughly 3 times more hematopoietic colonies were found to be formed than after transplantation of yolk sac cells of the quail embryo. With the dose of irradiation used, about 75% of exogenous (quail) and 25% of endogenous (chick) hematopoietic colonies were identified in the bone marrow.
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Latsis, R.V., Drize, N.I. & Derugina, E.I. Formation of hematopoietic colonies of donor's type in the bone marrow of irradiated chicks after transplantation of quail yolk sac and limb bud cells into their bone marrow. Bull Exp Biol Med 88, 1150–1153 (1979). https://doi.org/10.1007/BF00838191
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DOI: https://doi.org/10.1007/BF00838191