Bulletin of Experimental Biology and Medicine

, Volume 89, Issue 1, pp 10–12 | Cite as

Mechanism of disturbances of the contractile function of the masseter muscles in rats with experimental botulism

  • V. V. Mikhailov
  • N. É. Agaev
Pathological Physiology and General Pathology


Injection of a sublethal dose of botulinus toxin into one masseter muscle leads to unilateral paralysis of that muscle, accompanied by the development of biting. Membrane polarization and the amplitude of the action potential mainly of highly polarized muscle fibers are depressed in the paralyzed region, but the function of fibers with a low level of polarization is only slightly affected.

Key Words

electrogenesis in muscle fibers botulinus toxin masseter muscle biting 


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • V. V. Mikhailov
  • N. É. Agaev

There are no affiliations available

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