Mechanism of disturbances of the contractile function of the masseter muscles in rats with experimental botulism
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Injection of a sublethal dose of botulinus toxin into one masseter muscle leads to unilateral paralysis of that muscle, accompanied by the development of biting. Membrane polarization and the amplitude of the action potential mainly of highly polarized muscle fibers are depressed in the paralyzed region, but the function of fibers with a low level of polarization is only slightly affected.
Key Wordselectrogenesis in muscle fibers botulinus toxin masseter muscle biting
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- 1.N. E. Agaév, in: Diagnosis, Prevention, and Treatment of the Principal Stomatologic Diseases [in Russian], No. 2, Moscow (1978), p. 138.Google Scholar
- 2.V. V. Mikhailov, “On the pathophysiological mechanisms of experimental botulism,” Doctoral Dissertation, Moscow (1958).Google Scholar
- 3.V. V. Mikhailov and V. V. Morrison, Byull. Éksp. Biol. Med., No. 1, 25 (1973).Google Scholar
- 4.V. V. Mikhailov and V. Vas. Mikhailov, Byull. Éksp. Biol. Med., No. 11, 21 (1975).Google Scholar
- 5.V. V. Mikhailov and N. A. Sokolova, Vopr. Med. Khim., No. 6, 600 (1975).Google Scholar
- 6.D. B. Drachman, The Pathophysiological Actions of Neuropoisons, New York (1971), p. 25.Google Scholar
- 7.A. Grumbach, in: Die Infektionskrankheiten des Menschen und ihre Erreger, Stuttgart, Vol. 2 (1958), p. 973.Google Scholar
- 8.H.-W. Koeppe, in: Klinik der Gegenwart, Vol. 1, Munich (1955), p. 183.Google Scholar
- 9.D. A. Kauter and R. K. Lynt, Nutr. Rev.,31, 265 (1973).Google Scholar