Bulletin of Experimental Biology and Medicine

, Volume 80, Issue 5, pp 1376–1379 | Cite as

Myelin-like structures in heart muscle cells after administration of adrenalin

  • N. N. Kleimenova
  • E. E. Belen'kii
Morphology and Pathomorphology


The state of the heart muscle cells of 36 albino rats was studied experimentally after a single intramuscular injection of adrenalin hydrochloride (3 mg/kg) into the thigh. Electron-microscopic investigation of the heart muscle cells showed foci of overcontraction and overstretching of the myofibrils, as well as numerous myelin-like figures, often containing mitochondria and glycogen, and drops of lipids. It is postulated that the harmful action of adrenalin is manifested through the activation of lipolysis, leading to dissociation of the protein-lipid components of the mitochondrial membranes, the accumulation of fatty acids in the cytoplasm, and resynthesis of new and unusual membrane formations.

Key Words

adrenalin myocardium lipid metabolism 


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • N. N. Kleimenova
  • E. E. Belen'kii

There are no affiliations available

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