Abstract
The developing ova of the sea urchinStrongylocentrotus intermedius, at different stages of the first mitotic cycles, vary in their sensitivity to toxic concentrations of prostaglandin F2α and cyclic 3′,5′-AMP. Differences in sensitivity to each of these substances follow a similar and regular pattern and depend on the time elapsing after the preceding division. Two periods of increased sensitivity of the ova were found: the first, 20 min after completion of each division, to both substances and the second, after 40 min to cyclic AMP and after 50 min to prostaglandin.
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Additional information
All-Union Research Institute of Obstetrics and Gynecology, Ministry of Health of the USSR, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 11, pp. 87–90, November, 1975.
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Persianinov, L.S., Massal'skaya, L.M. Changes in sensitivity of developing sea urchin embryos to prostaglandin F2α and to cyclic AMP. Bull Exp Biol Med 80, 1362–1364 (1975). https://doi.org/10.1007/BF00835188
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DOI: https://doi.org/10.1007/BF00835188