Abstract
Intestinal tumors induced in rats by 1,2-dimethylhydrazine contain a water-soluble antigen that is absent in other organs and tissues, including in the mucous membranes of the intestines of control animals. This antigen can also be detected in embryos at the seventh and ninth days of development. In rats with intestinal tumors the antigen was found in 70% of cases in the blood serum. By analogy with human carcinoembryonic antigen, the rat antigen now discovered is soluble in 1 M perchloric acid.
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Okulov, V.B., Pozharisskii, K.M. Carcinoembryonic antigen of experimental intestinal tumors. Bull Exp Biol Med 80, 1352–1354 (1975). https://doi.org/10.1007/BF00835185
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DOI: https://doi.org/10.1007/BF00835185