Bulletin of Experimental Biology and Medicine

, Volume 80, Issue 5, pp 1347–1349 | Cite as

Characteristics of the specific antigen of burned skin

  • B. E. Movshev
Microbiology and Immunology


Antisera obtained by hyperimmunization of rabbits with preparations of high-molecular-weight proteins of burned and normal rat skin were tested in the agar diffusion test before and after exhaustion by normal skin and serum proteins. A single precipitation line was found in the composition of the specific test system on visual investigation. Increasing the sensitivity of the test by using microphotometry of stained preparations revealed the polycomponent nature of the system, in which, besides the specific antigen present in the highest titer, other antigen-antibody complexes are present. The specific antigen of burned skin has relatively weak immunogenic properties.

Key Words

burns specific antigen of burned skin immunogenicity 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    M. Horwitz and M. Scharff, in: Methods in Virology and Molecular Biology [Russian translation], Moscow (1972), p. 200.Google Scholar
  2. 2.
    A. I. Gusev and V. S. Tsvetkov, Lab. Delo, No. 2, 43 (1961).Google Scholar
  3. 3.
    I. I. Kolker, S. M. Vul', and A. P. Nevinnaya, Pat. Fiziol., No. 5, 52 (1970).Google Scholar
  4. 4.
    V. A. Mazurenko, in: Burns [in Russian], No. 1, Kiev (1966), p. 35.Google Scholar
  5. 5.
    B. E. Movshev, Byull. Éksp. Biol. Med., No. 9, 58 (1970).Google Scholar
  6. 6.
    B. E. Movshev, Pat. Fiziol., No. 1, 37 (1971).Google Scholar
  7. 7.
    B. E. Movshev and V. I. Averchenko, Byull. Éksp. Biol. Med., No. 2, 52 (1973).Google Scholar
  8. 8.
    S. V. Skurkovich, “Data on the pathological physiology and experimental treatment of burns”, Doctoral Dissertation, Moscow (1959).Google Scholar
  9. 9.
    N. A. Fedorov, in: The Problem of Trauma [in Russian], Moscow (1960), p. 94.Google Scholar
  10. 10.
    N. A. Fedorov, Proceedings of the Twelfth International Congress on Blood Transfusion [in Russian], Moscow (1972), p. 17.Google Scholar
  11. 11.
    N. A. Fedorov and S. V. Skurkovich, Khirurgiya, No. 9, 48 (1955).Google Scholar
  12. 12.
    N. A. Fedorov, S. V. Skurkovich, and V. B. Freiman, in: Current Problems in Immunology [in Russian], Moscow (1964), p. 312.Google Scholar
  13. 13.
    J. S. Baumstark, R. J. Laffin, and W. A. Bardawil, Arch. Biochem.,108, 514 (1964).Google Scholar
  14. 14.
    S. Hajek, Soud. Lék.,10, 31 (1965).Google Scholar
  15. 15.
    I. A. Holder and M. Jogan, Experientia,26, 1363 (1970).Google Scholar
  16. 16.
    K. Kano, F. Milgrom, and F. T. Rapaport, Proc. Soc. Exp. Biol. (New York),128, 1165 (1968).Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • B. E. Movshev

There are no affiliations available

Personalised recommendations