Abstract
Experiments on isolated rabbit and dog hearts involving synchronized recording of electrical activity of the right atrium, right ventricle, and tricuspid valve demonstrated the existence of functional connections between atrial, ventricular, and valvular depolarization. The dynamics of the spread of excitation in the heart was investigated during electrical stimulation of the atrioventricular valves. Impulses from a heterotopic focus of excitation localized in these valves were shown to be conducted to other parts of the heart and to lead to the development of cardiac arrhythmias.
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Literature Cited
N. N. Beskrovnova, V. V. Korolev, I. L. Kosharskaya, et al., in: Ultrastructural Aspects of Morphogenesis and Regeneration Under Normal and Pathological Conditions [in Russian], Moscow (1976), pp. 77–83.
N. N. Beskrovnova, V. V. Korolev, I. L. Kosharskaya, et al., Byull. Éksp. Biol. Med., No. 5, 600 (1977).
V. A. Makarychev, I. L. Kosharskaya, and L. S. Ul'yaninskii, Byull. Éksp. Biol. Med., No. 5, 517 (1976).
A. L. Bassett, A. L. Wit, J. J. Fenoglio, et al., Fed. Proc.,33, 445 (1974).
A. L. Bassett, J. J. Fenoglio, A. L. Wit, et al., Am. J. Physiol.,230, 1366 (1976).
J. J. Fenoglio, T. D. Pham, A. L. Wit, et al., Circulat. Res.,31, 417 (1972).
D. V. Priola, R. L. Fulton, L. M. Napolitano, et al., Am. J. Physiol.,216, 238 (1969).
D. V. Priola, C. Fellows, J. Moorehouse, et al., Am. J. Physiol.,219, 1647 (1970).
E. H. Sonnenblick, L. M. Napolitano, W. M. Daggett, et al., Circulat. Res.,21, 9 (1967).
A. L. Wit, J. J. Fenoglio, B. M. Wagner, et al., Circulat. Res.,32, 731 (1973).
A. L. Wit and P. F. Cranefield, Circulat. Res.,38, 85 (1976).
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Kosharskaya, I.L. Spread of excitation in the heart during electrical stimulation of the atrioventricular valves. Bull Exp Biol Med 87, 85–88 (1979). https://doi.org/10.1007/BF00833954
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DOI: https://doi.org/10.1007/BF00833954