Abstract
The intensity of motor activity and the serum level of protein-bound iodine (PBI) were investigated in 62 puppies aged from 1 to 12 months. During the first 4 months of life a parallel increase in motor activity and PBI of the puppies was observed. The increase in motor activity of puppies between the ages of 7 and 9 months was not accompanied by any increase in PBI. In hypothyroidism caused by methimazole in puppies aged 1 and 3 months increased motor activity was observed, whereas in animals aged 7 months it was reduced. A higher intensity of motor activity than in the control animals also was observed 1 month after the operation in puppies thyroidectomized at the ages of 1 and 3.5 months. The activity of puppies thyroidectomized at the age of 1 month was sharply reduced 2–4 months after the operation. In dogs thyroidectomized at the ages of 7.5 and 11.5 months, reduced activity was observed as early as 1 month after the operation. The data showing opposite effects of thyroid hormones on the behavior of puppies at different ages point to a complex relationship between motor activity and thyroid function.
Similar content being viewed by others
Literature Cited
N. M. Vavilova, in: Brain Development in Animals [in Russian], Leningrad (1969), p. 192.
A. A. Voitkevich, Dokl. Akad. Nauk SSSR,57, 737 (1947).
T. F. Komarova, in: Evolution of Functions in Ontogeny [in Russian], Leningrad (1972), p. 48.
L. I. Stavitskaya, in: Molecular and Functional Bases of Ontogeny [in Russian], Moscow (1970), p. 322.
G. S. Stepanov, Lab. Delo, No. 10, 594 (1965).
J. Corn, J. Genet, Psychol.,110, 169 (1967).
J. T. Eayrs, J. Endocrinol.,22, 409 (1961).
J. T. Eayrs and S. Levine, J. Endocrinol.,25, 505 (1963).
M. Hamburgh and L. B. Flexner, J. Neurochem.,1, 279 (1957).
Z. Martinec and J. Lat, Physiol. Bohemoslov.,17, 545 (1968).
N. B. Myant, in: Chemistry of Brain Development, New York (1971), p. 227.
S. Schapiro, Endocrinology,78, 527 (1966).
Rights and permissions
About this article
Cite this article
Komarova, T.F., Kassil', V.G. Thyroid function and motor activity in dogs during development. Bull Exp Biol Med 87, 81–84 (1979). https://doi.org/10.1007/BF00833953
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00833953