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The synthesis of the sodium salt of β-oxybutyric acid from the acetoacetic ester

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Summary

A method is described for preparing the sodium salt of β-oxybutyric acid from acetoacetic ester. The acetoacetic ester is reduced by aluminium amalgam in moist sulphuric acid, and the β-oxybutyric acid thus obtained is then saponified to form the sodium salt of β-oxybutyric acid. The yield is approximately 30%.

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Authors and Affiliations

  1. Laboratory of Biochemistry Institute of Pharmacology and Chemotherapy, AMN SSSR, Moscow

    M. N. Kondrashova & I. A. Shabanova

Authors
  1. M. N. Kondrashova
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  2. I. A. Shabanova
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Kondrashova, M.N., Shabanova, I.A. The synthesis of the sodium salt of β-oxybutyric acid from the acetoacetic ester. Bull Exp Biol Med 51, 736–737 (1961). https://doi.org/10.1007/BF00833904

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  • DOI: https://doi.org/10.1007/BF00833904

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