Bulletin of Experimental Biology and Medicine

, Volume 51, Issue 6, pp 707–709 | Cite as

The growth of a primary tumor (sarcoma M-1) during the training of rats to hypoxia in the low pressure chamber

  • G. N. Arkhipov


The effect of hypoxic training of rats on the growth of transplantable tumors (sarcoma M-1) was studied in experiments involving 161 animals. In training the rats at an “altitude” of 6,000 m, the tumor growth was delayed by 18.6 per cent. With the rise of the training “altitude” there is a progressively increasing development of the tumor growth-inhibiting mechanisms. At the maximal “altitude” of training (10,750m) the tumor growth inhibition reached 57.5%.


Public Health Primary Tumor Tumor Growth Sarcoma Growth Inhibition 


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Literature Cited

  1. 1.
    G. A. Vasil'ev. Byull. Éksper. Biol. i Med.45, 2 (1958) p. 46.Google Scholar
  2. 2.
    G. G. Korobkov. Trudy Saratovsk. Med. in-ta26 (1959) p. 69.Google Scholar
  3. 3.
    I. R. Petrov. On the Role of the Nervous System in Oxygen Starvation [in Russian] (Leningrad, 1952).Google Scholar
  4. 4.
    I. R. Petrov, Fiziol. Zhurn. SSSR41, 1 (1955) p. 9.Google Scholar
  5. 5.
    I. R. Petrov Gubler E. V. Vestn. Khir.74, 4 (1954) p. 34.Google Scholar
  6. 6.
    I. R. Petrov, Gubler E. V. From: The Physiology and Pathology of Respiration, Hypoxia and Oxygen Therapy [in Russian] (Kiev, 1958) p. 404.Google Scholar
  7. 7.
    E. N. Domontovich. Contributions to the Problem of Adaptation of the Animal Body to the Hypoxic Form of Oxygen Deficiency [in Russian] Doctor's Dissertation (Moscow, 1956).Google Scholar

Copyright information

© Consultants Bureau 1961

Authors and Affiliations

  • G. N. Arkhipov
    • 1
  1. 1.Laboratory of Experimental Pathology Institute of Normal and Pathological PhysiologyAcademy of Medical Sciences, USSRMoscow

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