Summary
The effect of mineral and glucocorticoid adrenocortical function on the pathology of trauma was studied in rats with autotransplanted glands.
Studies were made of behavior, survival time, temperature and blood.
It was found that during the first month after autografting, despite the recovery of the cortical structure of the adrenals, the resistance of the animals to trauma was reduced; this effect may be attributed to adrenocortical glucosteroid failure.
The shocked autografted animals also showed pronounced hypothermia, a thickening of the blood, and an intense leucocytosis.
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Literature Cited
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V. K. Kulagin, Byull. Eksptl. Biol. i Med., No. 6, 35 (1960).
V. K. Kulagin and D. Ya. Shurygin, Éksptl. Biol i Med., No. 9, 108 (1960).
C. J. Wiggers, Physiology of Shock (New York, 1950).
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Kulagin, V.K. The effect of the adrenals on shock. Bull Exp Biol Med 51, 677–679 (1961). https://doi.org/10.1007/BF00833889
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DOI: https://doi.org/10.1007/BF00833889