Summary
Recordings from single afferent vagal fibers were made after focal injury to the lungs and revealed the following alterations in pulmonary receptor activity: 1) temporary disappearance of stretch-receptor activity, evidently due to the transient collapse of the pulmonary area containing the receptor; 2) continuation of stretch receptor activity during expiration, evidently due to the development of focal emphysema in the receptor area; 3) the development of low amplitude activity during expiration, which was not recorded during expiration of the same volume prior to injury. The effect may very likely be explained by receptor sensitization caused by the injury. It is suggested that in addition to impulses from the pulmonary focus itself, the pathological impulses may originate from receptors beyond the focus, the effect being todisorganize rather than to intensify the discharge.
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Sergeeva, Z.N., Goryunova, T.I. & Frankshtein, S.I. Afferent impulses in single vagal fibers in pulmonary damage (the nature of pathological impulses). Bull Exp Biol Med 51, 665–668 (1961). https://doi.org/10.1007/BF00833886
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DOI: https://doi.org/10.1007/BF00833886