Advertisement

Pharmaceutical Chemistry Journal

, Volume 19, Issue 4, pp 245–251 | Cite as

Synthesis and pharmacological activity of α,β-unsaturated ketones of the imidazo[1,2-a]benzimidazole series

  • Yu. A. Zhdanov
  • G. V. Kovalev
  • V. A. Anisimova
  • A. A. Spasov
  • N. I. Avdyunina
  • V. G. Alekseeva
  • E. L. Korol'
  • I. A. Barchan
  • I. D. Ionov
  • V. V. Shaidrov
Search for New Drugs
  • 27 Downloads

Keywords

Organic Chemistry Ketone Benzimidazole Pharmacological Activity Benzimidazole Series 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    V. A. Anisimova, N. I. Avdyunina, A. M. Simonov, et al., Khim. Geterotsikl. Soedin., No. 12, 1660–1665 (1976).Google Scholar
  2. 2.
    V. A. Anisimova and A. M. Simonov, Khim. Geterotsikl. Soedin., No. 1, 68–70 (1980).Google Scholar
  3. 3.
    V. A. Anisimova and A. M. Simonov, Khim. Geterotsikl. Soedin., No. 1, 121–125 (1976).Google Scholar
  4. 4.
    Yu. A. Zhdanov, Yu. E. Alekseev, V. G. Alekseeva, et al., Dokl. Akad. Nauk SSSR,244, 1122–1124 (1979).Google Scholar
  5. 5.
    Yu. A. Zhdanov, Yu. E. Alekseev, et al., Zh. Obshch. Khim.,45, 1327–1333 (1975).Google Scholar
  6. 6.
    Ya. I. Zaidler, in: Modeling, Methods of Study, and the Experimental Therapy of Pathological Conditions [in Russian], Moscow (1967), Part 3, p. 191.Google Scholar
  7. 7.
    M. D. Mashkovskii, Drugs [in Russian], 8th edition, Moascow (1977), Part 1, pp. 383, 409.Google Scholar
  8. 8.
    A. M. Simonov and V. A. Anisimova, Khim. Geterotsikl. Soedin., No. 6, 1102–1104 (1968).Google Scholar
  9. 9.
    A. M. Simonov, V. A. Anisimova, and N. I. Avdyunina, Author's Certificate (USSR) No. 479,770, Otkrytiya, No. 29, 79 (1975).Google Scholar
  10. 10.
    A. M. Simonov, A. A. Belous, V. A. Anisimova, et al., Khim.-farm. Zh., No. 1, 7–10 (1969).Google Scholar
  11. 11.
    Ya. I. Khadzhai, G. V. Obolentseva, and A. P. Prokopenko, Farm. Toksikol., No. 2, 156 (1966).Google Scholar
  12. 12.
    R. L. Erskine and E. S. Waight, J. Chem. Soc., 3420 (1960).Google Scholar
  13. 13.
    W. B. Geiger and J. E. Conn, J. Am. Chem. Soc.,67, 112–116 (1945).Google Scholar
  14. 14.
    K. Iwarade, Bull. Chem. Soc. Japan,16, 40–44 (1941).Google Scholar
  15. 15.
    S. Katayama, H. Shionoya, and S. Ohtake, Microbiol. Immunol. (Tokyo),22, 89–101 (1978).Google Scholar
  16. 16.
    J. Koo, J. Org. Chem.,26, 4185 (1961).Google Scholar
  17. 17.
    R. Mecke and K. Noack, Ber. Chem. Ges.,93, 210 (1960).Google Scholar
  18. 18.
    German Patent No. 2,159,674 (1971); Chem. Abstr.,77, 140,078 (1972).Google Scholar
  19. 19.
    US Patent No. 2,728,784; Chem. Abstr.,50, 9043 (1956).Google Scholar
  20. 20.
    German Patent No. 919,128 (1954); Chem. Abstr.,52, 13,244 (1958).Google Scholar
  21. 21.
    J. J. Reyse, Br. J. Pharmacol.,3, 174–180 (1948).Google Scholar
  22. 22.
    E. Schraufstätter, Experientia,4, 484–5 (1948).Google Scholar
  23. 23.
    H. M. Vijay, G. Lavergne, H. Huang, et al., Int. Arch. Allergy,59, 277–82 (1979).Google Scholar
  24. 24.
    J. Wyczolkowska and C. Maslinski, Acta Allergol. (Kbh),31, 175 (1976).Google Scholar

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Yu. A. Zhdanov
    • 1
    • 2
    • 3
  • G. V. Kovalev
    • 1
    • 2
    • 3
  • V. A. Anisimova
    • 1
    • 2
    • 3
  • A. A. Spasov
    • 1
    • 2
    • 3
  • N. I. Avdyunina
    • 1
    • 2
    • 3
  • V. G. Alekseeva
    • 1
    • 2
    • 3
  • E. L. Korol'
    • 1
    • 2
    • 3
  • I. A. Barchan
    • 1
    • 2
    • 3
  • I. D. Ionov
    • 1
    • 2
    • 3
  • V. V. Shaidrov
    • 1
    • 2
    • 3
  1. 1.Research Institute for Physical and Organic ChemistryRostov UniversityUSSR
  2. 2.Volgograd Institute of MedicineUSSR
  3. 3.Research Institute for the Biological Testing of Chemical CompoundsMoscow Region

Personalised recommendations