Skip to main content
Log in

Proliferation of piriform neurons of the rat cerebellar cortex during pre- and postnatal development

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The method of histoautoradiography with thymidine-H3 was used to establish the times of appearance of neuroblasts, later differentiating into piriform neurons of the cerebellar cortex, in the anlage of the cerebellum and the dynamics of proliferative activity of these cells was studied in the course of pre- and postnatal development of the experimental animals. It was concluded from the results that the last divisions of cells differentiating into the Purkinje cells of the cerebellar cortex cease by the 13th–15th day of embryonic development. Later no more incorporation of labeled precursor into the nuclear DNA of the differentiating piriform neurons takes place.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. V. Ya. Brodskii, G. A. Sokolova, and T. E. Manakova, “Multiple increase in DNA in cerebellar Purkinje cells in rat ontogeny,” Ontogenez,2, No. 1, 33 (1971).

    Google Scholar 

  2. N. D. Gracheva, Autoradiography of Nucleic Acid and Protein Synthesis in the Nervous System [in Russian], Leningrad (1968).

  3. G. A. Nevmyvaka, “Investigation of DNA synthesis and the kinetics of cell populations during the development of the cerebellar cortex of albino rats,” in: Investigation of Cell Cycles and Nucleic Acid Metabolism during Differentiation of Cells [in Russian], Moscow-Leningrad (1964), pp. 107–115.

  4. J. Altman, J. Comp. Neurol.,136, 269 (1969).

    Google Scholar 

  5. C. D. Das and H. O. Normes, Z. Anat. Entwickl.-Gesch.,138, 155 (1972).

    Google Scholar 

  6. S. Fujita, J. Comp. Neurol.,122, 311 (1964).

    Google Scholar 

  7. S. Fujita, “Autoradiographic studies on histogenesis of the cerebellar cortex,” in: Neurobiology of Cerebellar Evolution and Development, Chicago (1969), pp. 743–747.

  8. R. J. Haas and J. J. Werner, Exp. Brain Res.,18, 59 (1973).

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Volkova, R.I. Proliferation of piriform neurons of the rat cerebellar cortex during pre- and postnatal development. Bull Exp Biol Med 80, 1259–1261 (1975). https://doi.org/10.1007/BF00833179

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00833179

Key Words

Navigation