Abstract
Early embryogenesis was studied cytologicaly in laboratory mice. Preimplantation embryonic mortality among DBA/2JY, C57BL/6JY, and 101/HY mice and among CBWA females crossed with B6 males did not exceed 4–6%. An exception was the AKR/JY mice, with a preimplantation mortality of 29.6%. Investigation of the nature of chemically induced dominant lethals showed that the arrest of cleavage and death of the embryos were caused by gross structural changes in the chromosomes.
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Semenov, K.K., Malashenko, A.M. Cytological study of early embryonic mortality in laboratory mice. Bull Exp Biol Med 80, 1249–1251 (1975). https://doi.org/10.1007/BF00833176
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DOI: https://doi.org/10.1007/BF00833176