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Stimulation of chloramphenicol acetyltransferase synthesis by cyclic AMP in bacterial cell systems

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of cyclic 3′,5′-adenosine monophosphate (cAMP) on production of the enzyme chloramphenicol acetyltransferase (CAT) by whole bacterial cells was studied in strainsEscherichia coli CSH-2/R222 and WZ-78/R222 (cya855). CAT synthesis in strainE. coli WZ-78/R222 was shown to have an intensity only half as great as that of strainE. coli CSH-2/R222. The production of CAT by strainE. coli CSH-2/R222 was increased only very slightly by cAMP, but its effect on the production of this enzyme in strain WZ-78/R222 was appreciable.

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Boichenko, M.N., Aniskin, E.D. Stimulation of chloramphenicol acetyltransferase synthesis by cyclic AMP in bacterial cell systems. Bull Exp Biol Med 80, 1203–1204 (1975). https://doi.org/10.1007/BF00833161

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  • DOI: https://doi.org/10.1007/BF00833161

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