Abstract
Reducing the motor activity of rats (for 20–100 days) in which the static function of the limbs is preserved leads to a marked decrease in thickness of the cortex of the femur. However, the ability of the whole bone to withstand mechanical loading is only slightly reduced. Thinning of the cortical layer is compensated by an increase in the strength of the bone tissue as a result of its increased mineralization.
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Mirolyubov, G.P., Korzhen'yants, V.A., Stupakov, G.P. et al. Effect of hypokinesia on the strength of bone. Bull Exp Biol Med 80, 1171–1173 (1975). https://doi.org/10.1007/BF00833149
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DOI: https://doi.org/10.1007/BF00833149