Abstract
The distribution of antibodies against a synthetic double-helical polynucleotide (polyI: polyC) was investigated. Antibodies against double-helical RNA were found in 14% of patients with allergoses and healthy subjects, in 40.9% of patients with rheumatic fever, and in 50% of patients with rheumatoid arthritis. It is postulated that the more frequent discovery of antibodies against double-helical RNA in the patients with rheumatic fever and rheumatoid arthritis is due to persistence of RNA-containing viruses.
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Zborovskii, A.B., Sidorova, N.M. Distribution of antibodies against double-helical RNA and ribosomal RNA in patients with allergoses, rheumatic fever, and rheumatoid arthritis. Bull Exp Biol Med 79, 440–442 (1975). https://doi.org/10.1007/BF00832721
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DOI: https://doi.org/10.1007/BF00832721