Abstract
Simultaneous injection of bone marrow antigenic cells incubated with “immune” RNA, thymus cells, and sheep's red cells into irradiated CBA or DBA/2 mice leads to greater accumulation of antibody-forming cells in the recipients' spleen than in mice injected with intact bone marrow cells or the same cells incubated with normal RNA. Pre-incubation of thymus cells with “immune” RNA does not cause any change in the accumulation of antibody-producing cells. Incubation of peritoneal exudate cells with “immune” or normal RNA like-wise had no effect on the character of accumulation of antibody-forming cells.
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Galaktinov, V.G., Morgunov, O.I., Smirnova, N.N. et al. Effect of “immune” RNA on cells of different types interacting in the immune response. Bull Exp Biol Med 79, 430–432 (1975). https://doi.org/10.1007/BF00832718
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DOI: https://doi.org/10.1007/BF00832718