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Effect of tetanus toxin on protein composition of synaptic structures of the rat brain and spinal cord

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

It was shown by electrophoresis on polyacrylamide gel that the content of proteins with low electrophoretic mobility rises in a Triton extract of the fractions of synaptic structures from the spinal cord tissue of rats with local tetanus, whereas no change was found in the protein spectrum in the dodecyl sulfate extract. In experiments in vitro tetanus toxin stimulated the incorporation of lysine-H3 into total proteins of cortical synaptosomes.

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Kryzhanovskii, G.N., Fedorova, V.I., Glebov, R.N. et al. Effect of tetanus toxin on protein composition of synaptic structures of the rat brain and spinal cord. Bull Exp Biol Med 79, 367–370 (1975). https://doi.org/10.1007/BF00832698

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  • DOI: https://doi.org/10.1007/BF00832698

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