Age differences in the hormonal response of the adrenals and testes to stress in monkeys
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Adrenal and testicular function of sexually immature and adult male baboons (Papiohamadryas) was investigated during immobilization stress. The concentrations of testosterone, 5α-dihydrotestosterone, hydrocortisone, and intermediate products of their biosynthesis — progesterone, pregnenolone, 17-hydroxyprogesterone, 17-hydroxypregnenolone, and 11-deoxycortisol — in the peripheral blood plasma of the monkeys were determined by a radioimmunological method. The main age differences in the character of the hormonal response to stress were shown to be the absence of changes in the blood androgen concentration of the immature animals and the smaller increase in the hydrocortisone concentration in them than in the adult monkeys. The concentrations of precursors of the steroid hormones fell considerably in the immature monkeys during stress, whereas in the adult animals their level rose 3–4-fold.
Key Wordsimmobilization stress steroid hormones sacred baboons
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