Bulletin of Experimental Biology and Medicine

, Volume 89, Issue 2, pp 127–130 | Cite as

Age differences in the hormonal response of the adrenals and testes to stress in monkeys

  • V. Yu. Butnev
  • L. P. Lomaya
  • A. G. Taranov
  • N. P. Goncharov
Pathological Physiology and General Pathology
  • 12 Downloads

Abstract

Adrenal and testicular function of sexually immature and adult male baboons (Papiohamadryas) was investigated during immobilization stress. The concentrations of testosterone, 5α-dihydrotestosterone, hydrocortisone, and intermediate products of their biosynthesis — progesterone, pregnenolone, 17-hydroxyprogesterone, 17-hydroxypregnenolone, and 11-deoxycortisol — in the peripheral blood plasma of the monkeys were determined by a radioimmunological method. The main age differences in the character of the hormonal response to stress were shown to be the absence of changes in the blood androgen concentration of the immature animals and the smaller increase in the hydrocortisone concentration in them than in the adult monkeys. The concentrations of precursors of the steroid hormones fell considerably in the immature monkeys during stress, whereas in the adult animals their level rose 3–4-fold.

Key Words

immobilization stress steroid hormones sacred baboons 

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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • V. Yu. Butnev
  • L. P. Lomaya
  • A. G. Taranov
  • N. P. Goncharov

There are no affiliations available

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