Induction of hypothermia by direct cooling of the brain through its external coverings
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The results of experiments with the isolated over-cooling of cats' brains are described. Deep hypothermia of the brain was achieved by its overcooling with the aid of “cold blankets”. During such over-cooling the temperature of the brain is decreased more rapidly and more deeply than rectal. There is a difference in temperature between the external and internal portions of the brain. Thus, at the termination of over-cooling the temperature equalled, on the average: in the external layer of the brain (in the cortex) 18°C, in the medial layer (subcortex) 21.2°C, at the base of the brain 24.7°C and in the rectum 29°C.
Reduction of the brain temperature is associated with changes in respiration and circulation. The following increase of the temperature results in recovery of these functions. Later, no pronounced disturbances were observed in these animals.
The method of over-cooling of the brain through the external surface of the head may be used in surgical practice.
KeywordsPublic Health External Surface Medial Layer External Layer Brain Temperature
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