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Experimental myocardial infarct in certain physiological and pathological states of the organism

Part 3. Effect of hypertension in the pulmonary circulation on the development of experimentally induced myocardial infarction

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

When the anterior descending coronary artery is ligated and there is a simultaneous narrowing of the puimonary artery or the rat emboli of the lungs the infarction usually spreatis to the anterior or, in certain cases, to the antero-lateral and the lateral wall of the right ventricle in rabbits. In certain cases there were noted, likiwise, the formation of the aneurysm of the right ventricle with advance of the process and appearance of fresh foci of necrosis and infiltration in the wall of the right ventricle. Thus, in the functional overstraining of the myocardium there is incoordination between the circulation of the blood and increased requirement of nutrition of the heart muscle. This brings about advancement of the process of myocaroial infarction with affection of the functionally overloaded areas of the myocardium.

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Authors and Affiliations

  1. Chair of Pathological Anatomy, I. M. Sechenov Order of Lenin 1st Moscow Medical Institute, Moscow, USSR

    S. A. Vinogradov

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  1. S. A. Vinogradov
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Vinogradov, S.A. Experimental myocardial infarct in certain physiological and pathological states of the organism. Bull Exp Biol Med 44, 1313–1317 (1957). https://doi.org/10.1007/BF00830621

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  • DOI: https://doi.org/10.1007/BF00830621

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