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The selective effect of some chemical stimulants on the reflexes from chemoreceptors

Communication VIII. The effect of streptomycin on reflexes from the chemoreceptors and mechanoreceptors of the pericardium

  • Pathological Physiology and General Pathology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Short-term experiments were performed on cats under urethan anesthesia. The effect of streptomycin administered parenterally on the reflexes from the pericardial chemoreceptors and mechanoreceptors was studied. Intravenous injection of streptomycin in the dose of 250,000–400,000 units and in intramuscular injection of 70,000–127,000 units completely depresses or considerably inhibits the reflexes from the pericardial chemoreceptors caused by nicotine. However, in the majority of experiments no depression of reflexes appearing in stimulation of pericardial mechanoreceptors was noted in similar experimental conditions. At times only an insignificant decrease of these reflexes was revealed.

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Authors and Affiliations

  1. The Laboratory of Experimental Pathology and Therapy of the Leningrad A. Ia. Shternberg Institute of Tuberculosis, Leningrad, USSR

    G. S. Kan

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  1. G. S. Kan
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Kan, G.S. The selective effect of some chemical stimulants on the reflexes from chemoreceptors. Bull Exp Biol Med 45, 696–700 (1958). https://doi.org/10.1007/BF00824587

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  • DOI: https://doi.org/10.1007/BF00824587

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