Skip to main content
SpringerLink
Log in

Changes in myocardial trophics during the chronotropic effect

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

An experimental study was carried out on the effect of rhythmic nerves (causing chronotropic effect) on the change of the cardiac rhythm and tissue respiration, the content of ATP, CP, inorganic phosphorus and glycogen. In positive chronotropic effect, resynthesis of ATP expended on contraction of the cardiac muscle takes place mainly by utilization of CP which is a reserve source of high-energy bonds both for the skeletal and the cardiac muscles. Therefore, the mechanical function of the heart depends on CP content.

In negative chronotropic effect the biochemical changes in the myocardium are insignificant.

In the authors' opinion the rhythmic nerves bring about certain quantitative changes of the biochemical indicaters which are the result of changes in conditions of cardiac function and not special and profound biochemical reorganization.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. A. V. Kibiakov, The Nature of the Regulatory Influence of the Sympathetic Nervous System In Russian. (Kazan, 1950).

  2. I. P. Pavlov, Collected Works, (Moscow-Leningrad, 1951), vol. 1, p. 432. in russian.

    Google Scholar 

  3. J. Chang, J. Physiol. 91, 314 (1937).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Normal Physiology, Kazan Medical Institute, Kazan, USSR

    N. M. Abramova, V. F. Anisimova, A. V. Gutovskaia, A. V. Kibiakov & Z. V. Urazaeva

Authors
  1. N. M. Abramova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. F. Anisimova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. V. Gutovskaia
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. V. Kibiakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Z. V. Urazaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Abramova, N.M., Anisimova, V.F., Gutovskaia, A.V. et al. Changes in myocardial trophics during the chronotropic effect. Bull Exp Biol Med 45, 667–669 (1958). https://doi.org/10.1007/BF00824580

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00824580

Keywords

Search

Navigation