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A new route for the synthesis of phenazine di-N-oxides

Ein neuer Syntheseweg für Phenazin-di-N-oxide

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary

Several phenazine 5,10-dioxides (7a–d) were prepared by the reaction of 2-methyl-3-acetylquinoxaline 1,4-dioxide (2) with different aromatic aldehydes or by direct cyclization of the quinoxaline cinnamoyl derivatives3 in basic medium. In addition, the phenazine derivatives8 and9–12 were synthesized by a one-pot reaction of substitutedo-nitroanilines with different hydroxy compounds in the presence of sodium hypochlorite solution.

Zusammenfassung

Mehrere Phenazin-5,10-dioxide (7a–d) wurden durch Reaktion von 2-Methyl-3-acetylchinoxalin-1,4-dioxid (2) mit verschiedenen aromatischen Aldehyden oder durch direkte Cyclisierung der Chinoxalinderivate3 in basischem Milieuhergestellt. Zusätzlich wurden die Phenazinderivate8 und9–12 in einer Eintopfreaktion von substituierteno-Nitroanilinen mit verschiedenen Hydroxyverbindungen in Gegenwart von Natriumhypochloritlösung synthetisiert.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Engineering, Ain Shams University, Cairo, Egypt

    M. S. Abd El-Halim

  2. Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt

    A. S. El-Ahl, H. A. Etman, M. M. Ali, A. Fouda & A. A. Fadda

Authors
  1. M. S. Abd El-Halim
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  2. A. S. El-Ahl
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  3. H. A. Etman
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  4. M. M. Ali
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  5. A. Fouda
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  6. A. A. Fadda
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Abd El-Halim, M.S., El-Ahl, A.S., Etman, H.A. et al. A new route for the synthesis of phenazine di-N-oxides. Monatsh Chem 126, 1217–1223 (1995). https://doi.org/10.1007/BF00824300

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  • DOI: https://doi.org/10.1007/BF00824300

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