Monatshefte für Chemie / Chemical Monthly

, Volume 122, Issue 11, pp 935–941 | Cite as

Improved syntheses of some monochloro- and monobromo-8-quinolinols

  • Herman Gershon
  • Donald D. Clarke
Organische Chemie Und Biochemie

Summary

Procedures were developed for the preparation of the 2-, 3-, 4-, and 6-monosubstituted chloro and bromo 8-quinolinols which afforded greater yields and/or reduced the number of steps in the preparation. 100 MHz1H-NMR spectra for the 12 possible monochloro and monobromo analogues are given.

Keywords

Monochloro-8-quinolinols Monobromo-8-quinolinols 2-Acetamido-5-halophenyl acetates 1H-NMR spectra 

Verbesserte Synthese von Monochlor- und Monobrom-8-chinolinolen

Zusammenfassung

Es wurden Verfahren entwickelt, um 2-, 3-, 4- und 6-Chlor bzw. -Brom-8-chinolinole in besseren Ausbeuten und/oder bei reduzierter Anzahl von Synthesestufen herzustellen. Die1H-NMR-Spektren der 12 möglichen Monochlor- und Monobromverbindungen werden angegeben.

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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Herman Gershon
    • 1
  • Donald D. Clarke
    • 1
  1. 1.Department of ChemistryFordham UniversityBronxUSA

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