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Synthese neuer mono- und dihalogenierter Salicylsäurederivate

Synthesis of novel mono- and dihalogenated salicylic acid derivatives

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Syntheses of 3- and 4-monohalogenated (2a, b; 3a–c; 4a–e) and 3,4-dihalogenated (4f–l) ethyl 5-cyano-salicylates are described. Nitration of the ethyl 5-cyano-4-halo-salicylates3a, b leads to the ethyl 5-cyano-4-halo-3-nitro-salicylates5a, b. Hydrolysis of the ester and cyano group as well as reactions of various chloroformates, N,N-dimethylcarbamyl chloride and acetic anhydride with the hydroxyl group have been studied.

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Authors and Affiliations

  1. Institut für Organische Chemie, Karl-Franzens-Universität Graz, A-8010, Graz, Österreich

    Hans-Werner Schmidt & Renate Dworczak

Authors
  1. Hans-Werner Schmidt
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  2. Renate Dworczak
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Schmidt, HW., Dworczak, R. Synthese neuer mono- und dihalogenierter Salicylsäurederivate. Monatsh Chem 117, 393–406 (1986). https://doi.org/10.1007/BF00816534

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  • DOI: https://doi.org/10.1007/BF00816534

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