Monatshefte für Chemie / Chemical Monthly

, Volume 115, Issue 12, pp 1453–1458 | Cite as

Zur Epoxidation der Δ 7-Doppelbindung in Vitamin D3 Röntgenstrukturanalyse des 4-Phenyl-1,2,4-triazolin-3,5-dion-Addukts — eine Strukturrevision

  • Christoph Kratky
  • Wolfgang Reischl
  • Erich Zbiral
Organische Chemie Und Biochemie

Epoxidation of the Δ 7-double bond of vitamin D3. X-ray structure determination of its 4-phenyl-1,2,4-triazolin-3,5-dione adduct. A structure revision

Abstract

Epoxidation of vitamin D3 withMCPBA yields exclusively the 7,8-monooxirane. Its 7R, 8R stereochemistry was established by X-ray analysis of thePTAD-adduct-derivative. This result corrects the stereochemical assignment in a previous publication7.

Keywords

Stereoselective epoxidation of vitamin D3 Stereochemistry of 7,8-epoxy-vitamin D3 

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • Christoph Kratky
    • 1
  • Wolfgang Reischl
    • 2
  • Erich Zbiral
    • 2
  1. 1.Institut für Physikalische ChemieUniversität GrazGrazÖsterreich
  2. 2.Institut für Organische ChemieUniversität WienWienÖsterreich

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