Journal of Neurology

, Volume 239, Issue 7, pp 404–406 | Cite as

Magnetic resonance imaging follow-up in Creutzfeldt-Jakob disease

  • Joachim Röthert
  • Andreas Schwartz
  • Michael Härle
  • Klaus Ulrich Wentz
  • Peter Berlit
  • Michael Hennerici
Original Communications
  • 24 Downloads

Summary

The history of a 67-year-old woman with histologically proven Creutzfeldt-Jakob disease (013) is presented. Before typical clinical and neurophysiological signs of CJD developed, magnetic resonance imaging (MRI) showed slightly enhanced signal intensity of the caudate nuclei and putamina in T2-weighted and proton density images, corresponding to spongiform degeneration in neuropathological examination. Five weeks later characteristical progressive cortical atrophy was demonstrated by follow-up MRI.

Key words

Creutzfeldt-Jakob disease Magnetic resonance imaging Putamen Globus pallidum Neuropathology 

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Joachim Röthert
    • 1
  • Andreas Schwartz
    • 1
  • Michael Härle
    • 2
  • Klaus Ulrich Wentz
    • 3
  • Peter Berlit
    • 1
  • Michael Hennerici
    • 1
  1. 1.Neurologische UniversitätsklinikGermany
  2. 2.Pathologisches InstitutGermany
  3. 3.Institut für Klinische RadiologieUniversität Heidelberg, Klinikum MannheimMannheimGermany

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