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Pyridazines with heteroatom substituents in position 3 and 5, part 1: 5-Hydroxy-3(2H)-pyridazinone and its derivatives

Pyridazine mit Heteroatomsubstituenten in Stellung 3 und 5, Teil 1: 5-Hydroxy-3(2H)-pyridazinon und seine Derivate

  • Organische Chemie Und Biochemie
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Summary

The synthesis of the title compound7 was achieved starting with mucochloric acidvia the pyridazinones1,2 and6. The electrolytic ionisation constants for7 were found to be 4.81 (±0.03) and −0.3 (±0.3). Crystal structure analyses were performed for7 and its “fixed” derivatives6 and9.

Zusammenfassung

Die Synthese der Titelverbindung7 via 1,2 und6 ausgehend von Mucochlorsäure wird beschrieben. DiepK-Werte von7 sind 4.81 (±0.03) und −0.3 (±0.3). Kristallstrukturanalysen von7,6, und9 wurden bestimmt.

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Authors and Affiliations

  1. Institut für Organische Chemie, Abteilung für Organische Synthese, Karl-Franzens-Universität Graz, A-8010, Graz, Austria

    Ulrike Gabriella Wagner & Thomas Kappe

  2. Institut für Physikalische Chemie, Karl-Franzens-Universität Graz, A-8010, Graz, Austria

    Ulrike Gabriella Wagner & Christoph Kratky

Authors
  1. Ulrike Gabriella Wagner
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  2. Christoph Kratky
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  3. Thomas Kappe
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Dedicated to Prof. Dr. Hans Junek on the occasion of his 60th birthday

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Wagner, U.G., Kratky, C. & Kappe, T. Pyridazines with heteroatom substituents in position 3 and 5, part 1: 5-Hydroxy-3(2H)-pyridazinone and its derivatives. Monatsh Chem 120, 329–342 (1989). https://doi.org/10.1007/BF00811746

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  • DOI: https://doi.org/10.1007/BF00811746

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