Catalysis Letters

, Volume 41, Issue 1–2, pp 111–112 | Cite as

Homogeneous asymmetric hydrogenation ofo-chloroacetophenone to enantiomerically pureo-chloro-(1-phenyl)ethanol catalyzed by BINAP-Ru(II) complex

  • Vilas H. Rane
  • Diedrik Tas
  • Rudy F. Parton
  • Peter A. Jacobs
Article

Abstract

The BINAP-Ru(II) catalyst (2,2′-bis(diphenylphosphino)-1,1′-binaphthyl)chloro(p-cymene)rutheniun chloride is found to be highly active and enantioselective for homogeneous asymmetric hydrogenation of o-chloroacetophenone to optically pureo-chloro-(1-phenyl)ethanol. In contrast to results of Noyori and coworkers, no organic and inorganic bases are required to obtain high activities and enantioselectivities

Keywords

enantioselective hydrogenation o-chloroacetophenone BINAP-Ru 

References

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Copyright information

© J.C. Baltzer AG, Science Publishers 1996

Authors and Affiliations

  • Vilas H. Rane
    • 1
  • Diedrik Tas
    • 1
  • Rudy F. Parton
    • 1
  • Peter A. Jacobs
    • 1
  1. 1.Department InterfasechemieCentrum voor Oppervlaktechemie en KatalyseHeverleeBelgium

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