Summary
Chick embryos underwent gamma-irradiation on the 5th day of incubation. Destruction of the endothelium and massive perivascular edema occur in the hematopoietic capillaries of the yolk-sac within the very first hours after irradiation. The hematopoietic elements disappear almost completely. Already on the next day, parallel with the continuing destruction, there appear regeneration elements in the form of proliferation of the reticuloendothelium and formation of new hematopoietic elements. Inhibition of the differentiation processes often leads to the accumulation of elements with low differentiation and prevents the restoration of normal blood composition. Marked effection of hematopoiesis leads in a number of cases to the reestablishment of megaloblastic hematopoiesis.
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Bursian, A.V. Peculiarities in the regeneration of the hematopoietic tissue in chick embryos exposed to externalγ-radiation. Bull Exp Biol Med 52, 852–855 (1961). https://doi.org/10.1007/BF00811651
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DOI: https://doi.org/10.1007/BF00811651