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Bulletin of Experimental Biology and Medicine

, Volume 52, Issue 1, pp 808–811 | Cite as

The glycogen content in the liver and muscles of rats in relation to the time elapsed after administration of chloropropamide and to the duration of fasting

  • S. G. Genes
  • L. M. Makarevich-Gal'perin
  • S. N. Ushenko
Pathological Physiology and General Pathology
  • 14 Downloads

Summary

A study was made of the effect of chloropropamide (100 mg per kg) on the blood sugar level and the content of glycogen in the liver and skeletal muscles of rats in 4,6,8,17,19,21,25,28,42 and 45 hours after the food intake was stopped and the preparation was administered. Marked reduction of the blood sugar level was noted for a period of 28 hours, whereas the glycogen content in the liver increased considerably only in 4,6 and 8 hours; in the muscles it increased in 8,17 and 19 hours. The content of glycogen in the liver and muscles depends not only on the chloropropamide action but also on the duration of the previous starvation.

Keywords

Public Health Sugar Skeletal Muscle Food Intake Blood Sugar 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1961

Authors and Affiliations

  • S. G. Genes
    • 1
  • L. M. Makarevich-Gal'perin
    • 1
  • S. N. Ushenko
    • 1
  1. 1.Ukrainian Institute of Experimental EndocrinologyKhar'kov

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