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The role of ascorbic acid in the mechanism of artificial hypothermia development

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The change of ascorbic acid content was studied in adrenal glands and blood of rabbits during the development of artificial hypothermia; changes occurring in the weight of adrenal glands were recorded as well. A reduction of ascorbic acid content in the adrenal glands takes place in conditions of moderate hypothermia at temperatures ranging from 31 to 26°C; there was also a moderate increase in the weight of the glands and a rise of ascorbic acid content in the blood. With intensification of hypothermia at temperatures ranging from 26 to 25°C a marked drop of ascorbic acid content in adrenal glands is accompanied by a reduction of their weight and discharge of ascorbic acid into the blood. In deep hypothermia (25–23°C) the amount of ascorbic acid in adrenal glands rises, their weight increases, while the blood ascorbic acid content declines.

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Ostashkov, K.V. The role of ascorbic acid in the mechanism of artificial hypothermia development. Bull Exp Biol Med 52, 797–800 (1961). https://doi.org/10.1007/BF00811637

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  • DOI: https://doi.org/10.1007/BF00811637

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