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Substituierte Methylphosphonate als Synthone für alicyclische α-funktionalisierte Phosphonate

Substituted methylphosphonates as synthons for alicyclic α-functionalized phosphonates

  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary

Syntheses of cycloalkylphosphonates4, and6–8 are described, starting from the substituted methylphosphonates1–3. Hydrolysis of the phosphonic esters4 and8 yield the free phosphonic acids5 and10; the partial hydrolysis of7 leads to easily accessible9. The benzo condensed phosphonates12 and13 are formed according to the solvent; a higher boiling medium should be used to obtain15 and17.

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Literatur

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Authors and Affiliations

  1. Pharmazeutisch-Chemisches Institut, Universität Heidelberg, D-W-6900, Heidelberg, Bundesrepublik Deutschland

    Richard Neidlein & Thomas Eichinger

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  1. Richard Neidlein
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  2. Thomas Eichinger
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Neidlein, R., Eichinger, T. Substituierte Methylphosphonate als Synthone für alicyclische α-funktionalisierte Phosphonate. Monatsh Chem 123, 1037–1043 (1992). https://doi.org/10.1007/BF00810935

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  • DOI: https://doi.org/10.1007/BF00810935

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